What is Endo-Sleeve?
The Endo-Sleeve procedure using the OverStitch Technology (also known as the Endoscopic Gastroplasty (ESG) technique) is a procedure to permanently reduce the size of the stomach and is suitable for individuals suffering with excess weight and obesity.

Performed while under anesthesia, the surgeon uses an endoscopic suturing device, entering the patient’s stomach via the mouth and esophagus to reduce the size of the stomach using gathered suture plications. The procedure closely replicates what would usually occur from a surgical sleeve gastrectomy, without the need for surgery. Unlike a surgical sleeve gastrectomy, the Endo-Sleeve procedure with the OverStitchTM Technology has a significantly lower risk of complications, faster recovery time, and is minimally invasive – therefore leaving no incisions or scars.
It is best suited for individuals with a BMI of 30 kg/m2 or more who have tried other weight loss programs, including conventional diet and exercise alone, but were unsuccessful.
Is the weight loss permanent?
Though the Endo-Sleeve procedure is a modern, safe, and effective weight loss procedure the question remains: Am I rid of excess weight permanently?
The most realistic answer is found in the study by Sharaiha, Reem Z., et al. “Five-Year Outcomes of Endoscopic Sleeve Gastroplasty for the Treatment of Obesity.” The study included 216 obese, or largely overweight with co-morbidities, patients.
It states that 90% of patients maintained a TBWL (Total body weight loss) of 5% or greater, and 74% of patients maintained an EWL (Excess weight loss) of 25% or greater after 5 years following the procedure, thus demonstrating the ENDO-SLEEVE procedure to be an effective weight loss intervention for the treatment of obesity.
This weight loss is significant because as little as 5% of weight loss can improve overall health and reduce the risk of obesity-related comorbidities, such as high cholesterol, type 2 diabetes, and cardiovascular disease. While the results of this study are promising for the success of long-term weight loss, further long-term studies are required.